Anybody else a trophy/achievement whore and live alone? It's totally possible to get this alone, it took me about 10 minutes to get the coordination down. I set my ION brain on the floor and held both guitars, and set the mic next to my tv (Apollo 13 FC'd Charlene several times just now).
If you have every instrument set to Super Easy on Charlene, and tap on the drum brain (or one of the pads, was easier for me to just tap my big toe on the circle button) to where you're hitting in the intro kick and red, and also a note in between (breaking your combo of course, but oh well, that speed occurs several times in the song, and just doing a constant beat takes less focus) then hit both strum bars to that beat as well once the notes start flowing in, you'll get an easy 100% on everything. You start getting close to dying on bass, but never fully go down. The health gained from hitting notes outdoes the massive amount of overstrums you'll take, but you'll be almost dead right as the song ends. It's nice and short too, so restarting isn't much of a hit.