For those who don't know, Talk Box is a piece of technology where you plug your guitar into it, and it ends up playing the guitar through the guitarist's mouth, who then actually "sings" the guitar into their mic, rather than traditionally playing the guitar through the amp. A few well-known examples:

Sweet Emotion by Aerosmith
Livin' on a Prayer by Bon Jovi
Several songs by Pink Floyd (this one is Keep Talking)

Different Rock Band and Guitar Hero songs have handled these differently. Man In the Box by Alice In Chains has the singer singing the talk box part in the opening. Livin' on a Prayer has the singer wait through the talk box parts.

So basically...how do you handle this when charting?