For the PS3 people that are just now getting Devin Townsed songs(and of course Xbox as well) I understand there can be some confusion if you start playing a random song and don't start with ZTO. Plus the fact that ZTO isn't on the PS3 doesn't help
So here's a rundown of the Ziltoid experiment.
Ziltoid (being the greatest guitar player that ever lived....or so he claims), discovers Rock Band and can't understand why us nerds are playing with plastic guitars.
So using a combination of Ziltoidian technology and coffee, Ziltoid beams himself directly into the programming of Rock Band to 'break the game', and general troll you while you try to play through the album.
If you ever notice the venue, lighting or camera spazz out that's Rock Band 'glitching' due to Ziltoid running rampant through the programming. He can also take direct control of the RB programming and cause the characters to behave strangely, scroll his own lyrics across the vocal chart, make things like odd solos appear at random times, cause the practice sections to scroll backwards, and of course bellow and yell at you over the music while you're trying to play.
That Ziltoid, what a little ****
Here this video will explain it better than I can :
http://youtu.be/sjUkDkHfxuc