Are there any guitar solos in songs that make you think "that doesn't really fit the music"? You can even expand it to keyboard or other solos if you want.
For me it's Zakk Wylde's solo in Black Label Society's In this River. It starts pretty well, but then he just starts shredding. Normally I wouldn't mind this, but when your doing a slower more emotional song backed by piano I don't think shredding is appropriate. I'm sure some of you like it, but I just didn't think it fits well.
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(solo starts at 2:30ish)